Learn more about Cinchona uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Cinchona. PubMed comprises more than 29 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to . Planta Med. Feb;80() doi: /s Epub Jan Cinchona alkaloids from Cinchona succirubra and Cinchona.

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Dutch colonialism and the origins of a global pharmaceutical industry”. One approach was to succiirubra the tree but this and girdling are equally destructive and unsustainable so small strips were cut and various techniques such as “mossing”, the application of moss to the cut areas, were used to allow the tree to heal.

Professor Cullen’s treatise of the materia medica. After Talbor’s death, the French king published this formula: The leaves have pubescent teeth that turn red when they are older, hence its nickname the red quinine tree.

The bark was dried into cinfhona were called quills and then powdered for medicinal uses. He proposed a Spanish expedition to search for plants of commercial value which was approved in and was continued after his death in by his nephew Sinforoso Mutis. Bulletin of the History of Medicine.


Cinchona alkaloids from Cinchona succirubra and Cinchona ledgeriana.

Lardner GibbonUSN. Its flowers form in large panicles. The species he described, Cinchona officinalis, was however found to be of little therapeutic value. They include a physical method and a chemical method.

Cinchona pubescens – Wikipedia

Role in the treatment of malaria”. Occurrence nature, food, other: A Gazetteer Compiled for Government Vol. Journal of the Linnean Society of London, Botany. The febrifugal properties of bark from trees now known to be in the genus Cinchona were used by many South American cultures [8] but malaria was an Old World disease that was introduced into the Americas by Europeans only after Sccirubra pubescens Vahl Cinchona pyrifolia L.

The synthesis of quinine inan increase in resistant forms of malaria, and alternate therapies ended the large-scale economic interest in their cultivation. In the late s, the method of use of the bark was noted in the Schedula Romana. The Indian Medical Gazette. Botanical expeditions — called Cinchona Missions [22] — were launched in to explore promising areas of South America in an effort to locate cinchona species that contained quinine and could be harvested for quinine production.

Retrieved 15 April A popular account of the introduction of Chinchona cultivation into British India.

The physical method involves manually felling adult trees and fully removing the stumps. The “fever tree” was finally described carefully by the astronomer Charles Marie de la Condamine who visited Quito in on a quest to measure an arc of the meridian.


Academic interest continues as cinchona alkaloids show promise in treating falciparum malaria which has evolved resistance to synthetic drugs. The barks of several species yield quinine and other alkaloids that were the only effective treatments against malaria during the height of colonialism which made them of great economic and political importance. There are four other classes of inferior bark, for some of which the bank pays fifteen dollars per quintal.

Cinchona alkaloids from Cinchona succirubra and Cinchona ledgeriana.

Cinchona pubescens Vahl In return, Talbor was offered membership of the prestigious Royal College of Physicians. For the role in establishing cinchona in Indonesia, Hasskarl was knighted with the Dutch order of the Lion.

Webarchive skccirubra wayback links Articles with ‘species’ microformats Articles with Spanish-language external links Articles with Portuguese-language external links Commons category link is on Wikidata Taxonbars with 20—24 taxon IDs.

Bulletin of the Institute of the History of Medicine. Please share your Comments. From Wikipedia, the free encyclopedia.