Sea como fuere, el tratamiento prolongado con nitratos se suele acompañar de En aquellos pacientes que presentan angina de Prinzmetal sobre un fondo de . We present 2 cases of severe vasospastic angina resistant to intensive medical vagal tone associated with thyrotoxicosis triggers prinzmetal variant angina and Un tratamiento a tener en cuenta en la tirotoxicosis inducida por amiodarona. S: Coronary arterial spasm and Prinzmetal’s variant form of angina induced by hyperventilation and Tris-buffer infusion. Circulation 56, A lead ECG was obtained. From the Cattedra di Fisiopatologia Cardiorespiratoria dell.

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Thyrotoxicosis-Induced Vasospastic Angina

The episodes of angina at rest were uncontrollable until diagnosis and proper treatment of the concomitant hyperthyroidism, the onset of which was nearly asymptomatic.

Thus, we highlight the importance of determining thyroid hormone concentrations in cases of vasospastic angina, especially when drug resistance is observed, 4 and even if the signs of hyperthyroidism are mild, 2 a circumstance to which previous treatment with beta-blockers can contribute.

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With a diagnosis of Graves’ disease, the hyperthyroidism was controlled with carbimazole, and the patient has remained asymptomatic after 8 months of follow-up with no need for calcium antagonists, which were discontinued 45 days after he was discharged.

He underwent primary angioplasty with conventional stent implantation in mid ADA. On the other hand, the control of hyperthyroidism proved impossible, despite the use of antithyroid drugs and the discontinuation of amiodarone. You can change the settings or obtain more information by clicking here. December Next article. Once the diagnosis of hyperthyroidism is established, medical treatment usually suffices, although, in severe cases, most of which are induced by amiodarone, thyroidectomy may be necessary.


Forty-eight hours later, a level of free thyroxine of 4. Calls from Spain 88 87 40 9 to 18 hours.

The duration of the follow-up period was prihzmetal months. Print Send to a friend Export reference Mendeley Statistics. Finally, the patient underwent total thyroidectomy, without subsequent recurrence of anginal episodes, even after the calcium antagonists were discontinued 2 months after the surgical procedure.

A repeated coronary angiography revealed a diffuse, severe spontaneous spasm of anterior descending artery ADA Figure 1which reproduced the admission clinical onset. These manuscripts contain updated topics with a major clinical or conceptual relevance in modern medicine.

We present 2 cases of severe vasospastic angina resistant to intensive medical treatment. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure prinzmeta the journal’s impact.

Three months after the procedure, he was readmitted with unstable angina after detection of transient precordial ST elevation and angjna enzymatic elevation. The atenolol that had originally been prescribed was discontinued.

For the management of this entity, it is essential to control ajgina thyroid activity, which can be curative in itself, obviating the need for subsequent antianginal therapy, 5 especially if there is no accompanying heart disease. Continuing navigation will be considered as acceptance of this use. The main characteristic of the initial clinical course was the difficult management, with frequent anginal episodes, despite the use of high-dose calcium antagonists and nitrates.

Previous article Next article. SRJ is a prestige metric based on the idea that not all citations are the same. The patient was a year-old man with dilated cardiomyopathy and angiographically normal coronary arteries in 2 prior catheterizations. Se continuar a navegar, consideramos que aceita o seu uso. Images subject to Copyright. Hospital General Universitario de Alicante.

Angina de Prinzmetal & Sd de Takotsubo by Diego Cañar on Prezi

The cardiovascular effects of hyperthyroidism are well known, and are associated with a hyperadrenergic state and an agonist effect of calcium in the myocardium.


The fisiopatologiq thyroxine level was 6. This item has received. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. Two weeks later, he was readmitted with the same clinical signs and symptoms and the same electrical changes, accompanied by anxiety and resting tremor.

This time, coronary angiography revealed diffuse spasm in mid-distal ADA Figure 2which was controlled with intracoronary nitroglycerin. Subscribe to our Newsletter. A anngina catheterization ruled out complications associated with the previously implanted stentas well a development of new lesions, and the patient was discharged on calcium antagonists and nitrates.

CiteScore measures average citations received per document published. The journal adheres to the standards of academic fisiopatolgia publications in all aspects including peer-review and ethical principles.

A year-old man was brought to our hospital with acute myocardial infarction and precordial ST elevation. The authors wish to thank the reviewers for their comments and the suggested modifications, which contributed considerably to improving the manuscript.

Previous Article Vol Iberoamerican Cardiovascular Journals Editors’ Network. Subscriber If you already have your login data, please click here. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. From Monday to Friday from 9 a.