IN William Heberden’s classic descrip- tion of angina his vivid portrayal of the symptoms of angina pectoris . The recognitioln of anginia pectoris is de-. William Heberden (13 August – 17 May ) was an English physician. Physicians) were papers on chickenpox () and angina pectoris (). His Commentarii de morborum historia et curatione, the result of notes made in his. Variant angina, often termed Prinzmetal’s angina, Prinzmetal angina and less commonly Dr. William Heberden is credited with being the first to describe in a .. idioventricular rhythm · Catecholaminergic polymorphic · Torsades de.

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However, the gold standard for diagnosing variant angina is to visualize coronary arteries by angiography before and after injection of a provocative agent such as ergonovinemethylergonovine or acetylcholine to precipitate an attack of vasospasm.

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During acute attacks, individuals typically respond well to fast-acting sublingual, intravenous, or spray nitroglycerin formulations. In he became a fellow of the Royal College of Physicians in London; and two years later he settled in London, where he was elected a fellow of the Royal Society inand enjoyed an extensive medical practice for more than thirty years.

Heberden in that it appeared due to episodic vasospasm of coronary arteries that were typically not occluded by pathological processes such as atherosclerosisembolior spontaneous dissection i. Thomas Vernon Wollaston entomologist and malacologist — As maintenance therapy, sublingual nitroglycerin tablets can be taken min before conducting activity that antina angina by the small percentage of patients who experience angina zngina and only when doing such activity.

Report of a six year experience”. In addition, aspirin should be used with caution and at low doses since at high doses it inhibits the production of the naturally occurring vasodilator, prostacyclin. Please help improve this article by adding citations to reliable sources.


William Heberden

The intake of certain agents have been reported to trigger an attack of variant angina. Accelerated idioventricular rhythm Catecholaminergic polymorphic Torsades de pointes.

Cardiac fibrosis Heart failure Diastolic heart failure Cardiac asthma Rheumatic fever. John Francis Fauquier bank director — Sufferers usually have repeated episodes of unexplained e. The plan was soon adopted, and three volumes were successively laid before the public.

Inhe recommended to the College of Physicians the first design of the Medical Transactions, in which he proposed to collect together such observations as might have occurred to any of their body, and were likely to illustrate the history or cure of diseases.

This section needs additional citations for verification. A variant form of angina pectoris”.

Myocarditis Chagas disease Cardiomyopathy Dilated Alcoholic Hypertrophic Restrictive Ahgina endocarditis Cardiac amyloidosis Endocardial fibroelastosis Arrhythmogenic right ventricular dysplasia. These episodes may be far more frequent than expected, cause myocardial ischemia i.

Variant angina

ECG changes compatible but not indicative of variant angina include elevations rather than depressions of the ST segment or an elevated ST segment plus a widening of the R wave to create a single, broad QRS complex peak termed the “monophasic curve”.

Charles Buller Heberden classical scholar and academic administrator — Atrial flutter Ventricular flutter Atrial fibrillation Familial Ventricular fibrillation. In contrast to patients with angina pectoris secondary to coronary artery atherosclerosis, people with variant angina are generally angian and have fewer risk factors for coronary artery disease except for smokingwhich is a common and very significant risk factor for both types of angina.

From Wikipedia, the free encyclopedia.

In other projects Wikimedia Commons Wikisource. Caroline Marianne Woods — Charles Buchanan Wollaston priest — George Wollaston priest — Alexander Richmond Wollaston surgeon and explorer — Smoke cessation significantly reduces the incidence of patient-reported variant angina attacks.


Wikisource has original works written by or about: Edward King Bishop of Lincoln — Some account of a disorder of the breast. Patients complaining of chest pain should be immediately checked for anyina abnormal electrocardiogram ECG.

Afflicted individuals should not smoke tobacco products. For his son, see William Heberden the Younger. Francis Fauquier governor abgina National Heart Lung and Blood Institute. Charles Earle Raven theology professor — Cardiac examination of individuals with variant angina is usually normal in the absence of current symptoms. Cardiovascular disease heart I00—I52— Archives of Cardiovascular Diseases.

Variant angina – Wikipedia

Of which indeed their frequent faintness and sensations as if all the powers of life were failing, afford no obscure intimation. Individuals who develop cardiac chest pain are generally treated empirically as an ” acute coronary syndrome “, and are immediately tested for elevations in their blood levels of enzymes such as creatine kinase isoenzymes or troponin that are markers for cardiac damage.

The pain is sometimes situated in the upper part, sometimes in the middle, sometimes in the bottom of the os. John Stevens Henslow priest, botanist and anginq — Sinus hbeerden Sick sinus syndrome Heart block: The seat of it and the sense of strangling and anxiety with which it is attended, may make it not improperly be called angina pectoris. Althea Hyde Wollaston — Alexander Luard Wollaston — Accordingly, individuals with variant angina should be intermittently evaluated for this using long-term ambulatory cardiac monitoring.

Stanley George Buchanan Wollaston — Maria Jane Gambier — Gerald Woods Wollaston herald —